Turmeric Compounds Regulate Factors Involved in Metabolic Syndrome Conditions

Turmeric compounds suppress the production of inflammatory molecules by cells that promote metabolic syndrome conditions. At the same time turmeric compounds promote beneficial factors that affect metabolism, such as: (vii.1, 8)

An additional benefit found in turmeric's curcumin compounds is the ability to behave in opposite ways, depending on the cell. So for instance, curcumin promotes PPAR-γ proteins in the liver to protect it from fatty liver disease, but suppresses it in fat cells to prevent fat cell growth and obesity. (vii.9)

Some examples of the effects of the factors on metabolic syndrome and how turmeric compounds activities can help include: (vii.1, 8, 10-16)

Adipocytes (fat cells), macrophages (immune system cells), liver, muscle, and pancreatic cells. (vii.1, 8-9)
Such as PPAR-γ. (vii.1)
Such as adiponectin. (vii.1)
For example, Nrf2, a transcription factor that triggers genes to make antioxidants. (vii.1)

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