Treatment for Human Papillomavirus (HPV)

Clinical Trial
Table V.21: Human Papillomavirus (HPV)
Turmeric's curcumin compounds may help treat HPV.

Human papillomavirus (HPV) is a sexually transmitted disease. Certain types of HPV increase the risk of cervical cancer. HPV may also promote head and neck squamous cell carcinoma, according to a number of research studies. (v.167-168)

Just being infected by HPV doesn't make cervical cancer a certainty — just as not all smokers develop lung cancer. However, unlike using tobacco, HPV is a necessary precondition for cervical cancer to develop. When cancer does develop, it's because HPV has activated transcription factor proteins that promote carcinogenic activity. (v.167-169)

Specifically, these proteins: (v.167)


Lab & Current Clinical Trial

  • Curcumin inhibits transcription factor proteins AP-1 and NF-κB by HPV 18. This prevents activation of oncogenes that transform normal cells in the cervix into precancerous lesions and cervical cancer. (v.169)
  • Lab tests show that a topical herbal cream ((Basant)) containing curcumin can stop HPV from getting into cervical cells. This could help women who are already infected with HPV from developing cervical cancer. (v.169)
  • In fact, a clinical trial is currently ongoing to test its effectiveness and safety in infected women with precancerous lesions. Basant also inhibits Candida fungal infections, HIV-1, and the bacteria that cause gonorrhea (in lab experiments). (v.169)
HPV-16 and HPV-18. (v167)

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