Insufficient Thyroid Hormone Linked to Alzheimer's Disease?

Turmeric can help regulate thyroid hormone levels, which may help reduce the risk of Alzheimer's disease.

Areas of the brain associated with learning and memory (e.g., the hippocampus and cerebral cortex) need thyroid hormone to function properly. Low levels of thyroid hormone are found in hypothyroidism, depression, and schizophrenia. All three disorders show varying degrees of impaired learning and memory. (iv.55)

Thyroid hormone affects the production of other chemicals in the brain related to memory and learning as well. It also plays a role in energy production in brain cells. Thyroid hormone deficiency could therefore contribute to Alzheimer's disease in the following ways (which fortunately turmeric may be able to counteract): (iv.5560-61)

Table IV.4: Hypothyroidism and Alzheimer's Disease
HYPOTHYROID BIOCHEMICAL CONDITION HOW IT EFFECTS THE BRAIN

Expression of Neurogranin

  • Thyroid hormone regulates production of this protein, which is involved in signaling in the brain. Neurogranin is important for neuron health and learning.
  • Animal studies show that mice that don't make neurogranin perform poorly on tests that measure their ability to learn.
  • Studies show that people with schizophrenia have low levels of neurogranin in the prefrontal cortex part of the brain. Further research uncovered a gene linking neurogranin production (which is regulated by thyroid hormone) and schizophrenia.

Blood Flow and Impaired Glucose Metabolism

  • Imaging studies in humans demonstrate that thyroid hormone deficiency reduces blood flow and metabolism of blood sugar in the brain.
  • Thyroid hormone helps regulate mitochondrial energy production (from glucose) in brain cells. Cell energy is crucial to maintaining a healthy antioxidant balance.
  • Even mild hypothyroidism results in memory deficits.
  • Functional magnetic resonance imaging (MRI) shows decreased brain activity in patients with lower than normal levels of thyroid hormone.

Acetylcholine (ACh) Production

  • ACh is a neurotransmitter that is essential to learning and memory. Not having enough thyroid hormone inhibits synthesis of ACh.
  • In animal studies, supplementing with thyroid hormone improved learning ability by increasing functional ACh.

Turmeric Can Counteract Low Thyroid Hormone Effects on the Brain

Low levels of thyroid hormone from hypothyroidism reduce production of the neurotransmitter acetylcholine (necessary for learning and memory) in the brain. Animal and human studies indicate that turmeric can help increase thyroid hormone in those with hypothyroidism. This suggests that turmeric may be able to: (iv.5560-62)

  • Counteract the contributing effects of hypothyroidism to Alzheimer's.
  • Improve impaired brain function and cognitive abilities in hypothyroid patients with Alzheimer's disease.
Calcium-related. (iv.60-61)
Biochemical substance that allows transmission of messages from the brain cells to the body. (iv.32)

Join the 1000s of People Who Are Discovering the Benefits of Turmeric.



New Vegan, Cruelty Free, Non GMO, Stearate Free, Gluten Free Turmeric Health Supplement Made in the USA in a GMP-certified, FDA-approved facility.

Healthceuticals® Turmeric Curcumin Complex

100% Certified
Organic ingredients

  • Organic Turmeric Extract - standardized to 95% curcuminoids.
  • Organic Whole Turmeric - provides full spectrum antioxidant, anti-inflammatory turmeric benefits, including turmerones and numerous vitamins, minerals, and phytonutrients
  • Organic Black Pepper Extract - standardized to 95% piperine; dramatically enhances bioavailablity.
  • Organic Phospholipids - markedly improve absorption.
  • Organic Ginger - works synergistically with turmeric to provide more powerful benefits.
  • Absolutely FREE of potentially harmful additives and fillers such as magnesium stearate.
Vegan | Cruelty Free | Non GMO | Stearate Free | Gluten Free Made in the USA in a GMP-certified, FDA-approved facility
Disclaimer: This website is not intended to replace professional consultation, diagnosis, or treatment by a licensed physician. If you require any medical related advice, contact your physician promptly. Information at this website is exclusively of a general reference nature. Do not disregard medical advice or delay treatment as a result of accessing information at this site.