What Are Growth Factors and Receptors?

Turmeric can help regulate growth factors and receptors that help cells grow and divide, including brain cells.

Growth factors and their receptors promote cell growth. They stimulate progression through the cell cycle, allowing replication and proliferation of cells. (iii.50-52)

Growth factors such as VEGF and BFGF also play a vital role in angiogenesis and are often referred to as angiogenesis factors. Angiogenesis is the scientific term for the development of new blood vessels. It's how the body responds to a long-term increased need for oxygen and nutrients in a specific area. For example, angiogenesis is a beneficial response to a clogged artery or other loss of circulation. (iii.50-52)

What Happens if Growth Factors and Receptors Are Unregulated?

Abnormal expression of these proteins can enhance tumor growth, while inhibiting them suppresses it. (iii.12153)

Sometimes angiogenesis stimulated by growth factors is detrimental. For example, tumor growth often strains the existing blood supply. Angiogenesis in cancer can promote metastasis, or the spread of cancer to other parts of the body. (iii.50-52)

Effects of Turmeric Curcumin Compounds on Growth Factors and Receptors

Studies show that the curcumin in turmeric is a potent inhibitor of many growth factors and receptors. By blocking these angiogenesis factors, curcumin can help stop tumors from metastasizing(iii.12153)

On the flip side, curcumin stimulates expression of BDNF (brain derived neurotrophic factor growth factor). BDNF protects and promotes development of healthy neurons (neurogenesis) in the central nervous system. Stimulating BDNF may: (iii.4354)

In fact pharmaceutical antidepressants stimulate neurogenesis to produce desired behavioral effects. (iii.4354)

However, curcumin doesn't always increase BDNF. In some instances the turmeric compound inhibits the growth factor. For example, chronic morphine treatment promotes overstimulated, high levels of BDNF. This leads to morphine tolerance and addiction and decreases morphine's effectiveness as a pain reliever. (iii.55)

Animal studies show that co-treatment with curcumin can help prevent this tolerance by suppressing increased BDNF activity. Curcumin also enhanced pain relief by activating both opioid and non-opioid receptors. (iii.55)

When the body has a short-term need for more oxygen/nutrients, such as when exercising, the heart is stimulated to pump faster and existing blood vessels dilate temporarily. (iii.51)

Join the 1000s of People Who Are Discovering the Benefits of Turmeric.

New Vegan, Cruelty Free, Non GMO, Stearate Free, Gluten Free Turmeric Health Supplement Made in the USA in a GMP-certified, FDA-approved facility.

Healthceuticals® Turmeric Curcumin Complex

100% Certified
Organic ingredients

  • Organic Turmeric Extract - standardized to 95% curcuminoids.
  • Organic Whole Turmeric - provides full spectrum antioxidant, anti-inflammatory turmeric benefits, including turmerones and numerous vitamins, minerals, and phytonutrients
  • Organic Black Pepper Extract - standardized to 95% piperine; dramatically enhances bioavailablity.
  • Organic Phospholipids - markedly improve absorption.
  • Organic Ginger - works synergistically with turmeric to provide more powerful benefits.
  • Absolutely FREE of potentially harmful additives and fillers such as magnesium stearate.
Vegan | Cruelty Free | Non GMO | Stearate Free | Gluten Free Made in the USA in a GMP-certified, FDA-approved facility
Disclaimer: This website is not intended to replace professional consultation, diagnosis, or treatment by a licensed physician. If you require any medical related advice, contact your physician promptly. Information at this website is exclusively of a general reference nature. Do not disregard medical advice or delay treatment as a result of accessing information at this site.