What Are Cyclin Growth Cycle Proteins?

Cyclins are necessary for cell growth and division.

A cell multiplies, or proliferates, by growing and dividing into two copies of itself. Cyclins are responsible for moving a cell through the various phases of cell cycle growth and replication. (iii.414)

Figure III.4: Cyclin Growth Cycle Proteins

Cyclin Growth Cycle Proteins

Effects of Turmeric and Turmeric Compounds on Cyclins

Chronic inflammation and oxidative stress and damage from free radicals can cause unregulated production of cyclins, leading to uncontrolled cell growth and proliferation (such as in cancer). Curcumin and its derivatives (e.g., HBC) inhibit or stimulate proteins that directly and indirectly block or promote cyclins. (iii.1449)

4-[3,5-bis-[2-(4-hydroxy- 3-methoxy-phenyl)-ethyl]-4,5-dihydro-pyrazol-1-y l]-benzoic acid. (iii.14)

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