Turmeric Compounds Help Suppress White Fat's Dangerous Activity
The type of fat found in patients with obesity is particularly dangerous to health. White adipose tissue (WAT), or white fat, actively causes inflammation. The chronic inflammation of obesity is fertile ground for metabolic syndrome diseases. (vii.2, 40)
How Can Turmeric Help?
Turmeric helps prevent and reduce chronic inflammation by blocking the proteins that cause it. In particular, natural compounds in turmeric block two of the main transcription factor proteins involved in inflammation and metabolic syndrome. (vii.1)
|What Activates NF-κB?|
|Effects on Metabolic Syndrome|
|What Turns NF-κB Off?|
|What Activates TNF-α?|
|Effects on Metabolic Syndrome||
|What Turns TNF-α Off?|
C-Reactive Protein (CRP)
Some of turmeric's compounds also reduce c-reactive protein (CRP), a protein produced by the liver if there's inflammation in the body. Highly sensitive tests conducted to measure levels of CRP are used to predict risk of heart disease. Reducing CRP prevents overproduction of endothelial adhesion molecules that cause: (vii.31, 44)
|Effect||↓ NF-κB||↓ TNF-α||↓ CRP|
|1,8-cineole (vii.29, 45)||♦|
|Alpha-linolenic acid (vii.2, 18, 22, 46)||♦||♦||♦|
|Alpha-terpineol (vii.20, 45)||♦||♦|
|Beta-sitosterol (vii.22, 29)||♦||♦|
|Borneol (vii.20, 45, 47)||♦||♦|
|Caffeic acid (vii.20, 48-50)||♦||♦|
|Curcumin (vii.21, 49, 51-53)||♦||♦||♦|
|Eugenol (vii.20-21, 26)||♦||♦|
|Ferulic acid (vii.47, 54)||♦|
|Fisetin (vii.25, 55)||♦||♦|
|Geraniol (vii.45, 56)||♦||♦|
|Limonene (vii.20, 45)||♦||♦|
|Myricetin (vii.25, 57)||♦|
|Niacin (vii.29, 58-59)||♦||♦||♦|
|Quercetin (vii.25-26, 50)||♦||♦|
|Resveratrol (vii.24, 27, 49, 60)||♦||♦|
|Vitamin C (vii.29, 50, 61)||♦||♦|
|Vitamin E (vii.29, 50, 61)||♦||♦|
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