DHT: The Super-Hormone Factor
Testosterone is an androgen hormone. A related androgen, dihydrotestosterone, is literally testosterone on steroids. 5α-reductase, a steroidal enzyme, metabolizes testosterone into DHT, a more powerful androgen. (x.108)
What Makes DHT More Potent Than Testosterone?
In order for testosterone or DHT to work, they must bind to an androgen receptor on a cell. DHT binds to the same androgen receptors on cells as testosterone does. However, DHT's bonds are stronger and last longer than testosterone, which makes its effects more powerful. (x.108)
Is DHT Harmful?
Within normal limits, DHT is a necessary hormone. However, too much DHT can cause or contribute to a number of diseases and/or conditions. These include: (x.100, 108)
- Acne
- Abnormal hair growth
- Bladder cancer
- Male balding
- Benign prostate hyperplasia
- Prostate cancer
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