Herbal Help to Prevent and Treat Lung Cancer

Fight Lung Cancer with the Antitumor Effects of Turmeric

Cancer in the lungs is one of the most common types of cancer worldwide. It's also a leading cause of death related to cancer. (vi.181)

So what can be done? Research suggests that turmeric and its compounds may be able to help prevent lung cancer. Turmeric's powerful curcumin pigments could even improve the effectiveness of chemotherapy, or act as a second line of therapy. (vi.1791345-347)

Types of Lung Cancer and Difficulties Treating

There are different types of cancer that affect the lung and the sacs that surrounding them, such as pleural mesothelioma and non-small-cell lung cancer (NSCLC). Some types of thoracic cancers are more aggressive than others, and they can develop resistance to conventional treatments. (vi.181345-346)

Different forms within these aggressive types also don't respond well to treatment. Some examples of this include:

  • NSCLC with certain gene mutations, which is resistant to the chemotherapy drug gefitinib. (vi.345)
  • Drug resistant malignant pleural mesothelioma, which doesn't respond to first line platinum-based chemotherapy drugs. (vi.346)

Early diagnosis of lung cancer is difficult since it's usually symptomless in the beginning. Although there have been advances in treatment for lung cancer, the long-term prognosis remains grim. Survival rates at 5 years after diagnosis are less than 15%. (vi.347)

How Turmeric Works Against Lung Cancer

Research suggests turmeric and its phytochemical compounds and nutrients can have beneficial preventive and therapeutic effects against lung cancer. These include:

Table VI.40: Turmeric's Phytochemical and Nutrient Effects in Lung Cancer
Turmeric Compound/Form Effects

Cinnamic acid (vi.74)

  • Stopped growth of lung adenocarcinoma cells. (vi.78)

Curcumin (vi.74)

Farnesol (vi.110)

Geraniol (vi.112)

Fisetin (vi.79)

Limonene (vi.74)

Myricetin (vi.79)

  • Growth of lung cancer cells. (vi.194)
  • Cytotoxic to lung cancer cells. (vi.194)

Quercetin (vi.79)

In a prospective study involving 41,000 American women, quercetin intake was associated with lower risk of lung cancer. Both smokers and non-smokers who ate diets high in leafy green vegetables containing quercetin had significantly less incidence of lung cancer. (vi.250)

This population study is supported by research that shows quercetin has the following effects on factors that contribute to lung cancer:

Resveratrol (vi.83)

Turmeric and Turmeric Oil

  • Turmeric oil prevents growth of lung cancer cells. (vi.91)
  • 1.5 g/day of turmeric for 30 days in 16 chronic smokers prevented formation and excretion of mutagens from carcinogens in cigarettes. (vi.17)

Vitamin C (vi.71)

Figure VI.25 - How Turmeric Compound Stop Lung Cancer Cells

Figure VI.25: How Turmeric Compounds Stop Lung Cancer Cells (vi.2178191111140275346350-354)

Does Curcumin Increase the Risks from Lung Cancer?

In one animal study using female C57BL/6 mice, 2-4% dietary curcumin increased the size and volume of metastatic lung tumors. Interestingly, in males of the same species of mice, 5% dietary curcumin complexes reduced the size of implanted lung tumors. Curcumin also enhanced the effects of the chemotherapy drug gemcitabine in that study. And when combined with catechin, curcumin significantly reduced lung metastasis from melanoma in female C57BL/6 mice. (vi.351355-356)

First responders that trigger gene activity. (vi.39)
Control switches for phases of the cell growth cycle. (vi.106)
Such as NF-κB, STAT-1, and STAT-3. (vi.2275346350)
Specifically, MMPs and fibroblast growth factor receptor (FGFR) tyrosine kinases. (vi.351-352)
Multidrug resistance. (vi.181)
Specifically, EGFR and miR-186. (vi.346)
Specifically, p21 and p27. (vi.78111)
Specifically, P21. (vi.111)
Including non-small cell lung cancer cells. (vi.140)
Such as survivin, an inhibitor of apoptosis type of cell death. (vi.140)

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